jinko-model

Jinkō Model SDK Workflows

Use this skill for technical model construction and editing through the SDK. Keep the scope on SDK mechanics and model validity, not biological plausibility. Initialize the connection with jinko-sdk-setup first.

PREREQUISITE: This skill needs an initialized jinko-sdk connection and an SDK satisfying its metadata.requires_sdk range. Run the jinko-sdk-setup skill (../jinko-sdk-setup/SKILL.md) and proceed only once its check passes. If that skill is not found, install it from novainsilico/jinko-skills.

Required Workflow

1. If a model was already supplied, prefer editing it over creating a new one. Create one only when needed, in a dedicated folder, with client.create_empty_model().

2. Retrieve the model, inspect its components, tags, units, solving options, and diagnostics before proposing edits. Inspect the unit-checking mode with model.get_unit_check().

3. Set the unit-checking mode with model.set_unit_check("UnitCheckAndConvertAllSpeciesToExtentUnits"). Do not select another mode unless a human explicitly directs it after the consequences are explained.

4. Give every directly declared numeric value a unit: numeric parameter formulas, compartment volumes, and species initial conditions. A parameter whose value is derived from an expression may omit its declared unit when the expression determines it. Validate non-trivial units against references/units_static_info.json and diagnostics.

5. Attach the built-in platform tags before considering the model complete:

   • i::vpop for inputs that vary across virtual patients.
   • i::protocol for inputs that vary across protocol arms or scenarios, including the dose amount, first dose time, dose interval, and number of doses of a dosing event.
   • One evidence-backed source tag for each applicable value-bearing input: s::knowledge, s::arbitrary, or s::to-calibrate. Leave an uncertain input untagged and report it for review. Never assign s::calibrated during construction; it records an accepted calibration result.
   • output for important time-series outputs to plot or calibrate against.

   Three of these decide whether the model is usable downstream, so check them across the whole model, not only per component. At least one component must carry output, or nothing can be plotted, measured, or calibrated against: treat its absence as an error. No component carrying i::protocol means the model cannot be given protocol arms, and none carrying i::vpop means it cannot vary across virtual patients: report each as a warning, correct only for a model meant to be single-arm and deterministic. python -m jinko.cli.validate_model_readiness --model-sid cm-... runs these three checks by default.

6. Attach a traceability link to every value-bearing input tagged s::knowledge. Prefer, in this order: the Extract that holds the value, the Reference that holds the Extract, then any other project item that produced the value. Use an external DOI or URL only when the project holds no such item, and report every external link for review. Use the jinko-reference skill to upload a missing source and to create its extracts in a dedicated literature subfolder before you link.

7. Use high-level SDK methods and model.components.batch(version="...") for related component changes. The platform tags above already exist; do not recreate them. Create declarations only for other, custom tags.

8. Re-fetch the model, require no error diagnostics, and run simple_solve() for representative output components. For events, verify the expected pre-/post-event change.

Use scripts/create_minimal_model.py, and the SDK's python -m jinko.cli.tag_model_components and python -m jinko.cli.validate_model_readiness, rather than long ad-hoc snippets. Scripts are dry-run by default and mutate only with --apply.

For transparent ISO 8601 duration conversions, use from jinko.iso8601 import Duration, for example Duration.parse("P1M").to_timedelta(). Solving times accept timedelta or ISO strings: model.set_solving_times(t_max=timedelta(days=28), t_step="P1D", additional_periods=[{"t_max": "P7D", "t_step": timedelta(hours=1)}]).

Reference Routing

• Read references/model-components.md for component batching, tags, events, formulas, and algebraic rules.
• Read references/unit_docs.md for unit semantics and conversion behavior.
• Read references/model-validation.md for diagnostics and readiness checks.